Sikeston Hotels with

Large illuminating lights and contemporary decor welcome you to the Holiday Inn Express & Suites Sikeston. Our hotel’s address in Sikeston, MO surrounds you with fun and nearby attractions. Thanks to a convenient location close to I55,I60 and nearby companies, including, Monsanto, Cargill, and Siemens, John Deere, Orgill, Tyson, Unilever and Sikeston Power Plant. In addition, we provide guests with a selection of handy services at our state of the art Business Center. Sikeston is also home to the annual Sikeston Jaycee Bootheel Rodeo, which draws large crowds every August.Our accommodations are close to shops and dining venues. Whether you’re staying in Sikeston, MO for business or pleasure, we have the amenities to satisfy your needs. Connecting to colleagues and family is easy with the free high speed Internet access, and mornings are great with a cup of fresh coffee and gooey cinnamon roll from our complimentary, hot Express Start breakfast bar. Go for a dip in the indoor heated pool or burn calories in our state of the art Fitness Center. If you are looking for lodging in Sikeston, MO, our hotel is the smart choice.

Settle in for a relaxing stay at the Sikeston’s newest hotel. Our Hampton Inn Sikeston hotel is located off Highway 60 and Interstate 55, just minutes from historic downtown and within walking distance to many shops and restaurants.Settle in for a relaxing stay in one of our modern guest rooms. Enjoy the convenience of a mini-refrigerator, microwave, free WiFi, coffeemaker, 42-inch flat-screen TV with premium cable channels and work desk with ergonomic chair. Upgrade to a studio suite for extra space and a separate seating area. Start each day with our free hot breakfast or, if you’re in a hurry, grab one of Hampton’s On the Run™ Breakfast Bags, available Monday through Friday. Stop by our Treats Shop any time of day or night for a quick snack or beverage. Stay in shape with a workout in our 24-hour fitness center or take a dip in our indoor heated pool. Plan a meeting in our 700 sq. ft. of meeting space fully equipped with A/V equipment.